CYP2D6 Antibody 0 Publications

Rabbit Polyclonal| Catalog number: 17868-1-AP

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Con: 51 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
mouse liver tissue

Positive IHC detected in:
human kidney tissue, human kidney tissue, human liver tissue

Recommended dilution:
WB : 1:200-1:1000
IHC : 1:20-1:200

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
cytochrome P450, family 2, subfamily D, polypeptide 6

Calculated molecular weight:
497aa,56 kDa

Observed molecular weight:
50 kDa,65 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
CYP2D6

Synonyms
CPD6, CYP2D, CYP2D@, CYP2D6, CYP2DL1, Cytochrome P450 2D6, P450 DB1, P450C2D, P450DB1
Background

CYP2D6(Cytochrome P450 2D6) is also named as CYP2DL1 and belongs to the cytochrome P450 family. It is a monooxygenase that involved in the metabolism of drugs such as antiarrhythmics, adrenoceptor antagonists, and tricyclic antidepressants. CYP2D6 is responsible for the metabolism of many drugs and environmental chemicals that it oxidizes. It has 2 isoforms produced by alternative splicing with the molecular weight of 56 kDa and 50 kDa.


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