DCTD Antibody 0 Publications

Rabbit Polyclonal| Catalog number: 16784-1-AP

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Con: 34 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
human brain tissue, PC-3 cells

Positive IF detected in:
HepG2 cells

Recommended dilution:
WB : 1:500-1:2000
IF : 1:10-1:100

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
dCMP deaminase

Calculated molecular weight:
178aa,20 kDa

Observed molecular weight:
20kd

GenBank accession number:

Gene ID (NCBI):

Gene symbol
DCTD

Synonyms
dCMP deaminase, DCTD, Deoxycytidylate deaminase
Background

DCTD(Deoxycytidylate deaminase) is also named as dCMP deaminase and belongs to the cytidine and deoxycytidylate deaminase family. It catalyzes the deamination of dCMP to dUMP, thus providing the nucleotide substrate for thymidylate synthase. Control of deaminase activity at this juncture in deoxyribonucleotide metabolism is determined by the ratio of dCTP to dTTP in the cell, since the enzyme is allosterically activated by dCTP and inhibited by dTTP(PMID:7685356). It has 2 isoforms produced by alternative splicing and can exsit as a dimer(pMID:8798492).


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