DDB2 Antibody 1 Publications

Rabbit Polyclonal| Catalog number: 10431-1-AP

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Con: 26 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
HeLa cells, A431 cells

Positive IF detected in:
HeLa cells

Recommended dilution:
WB : 1:500-1:2000
IF : 1:20-1:200

Product Information


Purification method:
Antigen affinity purification


PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information

Full name:
damage-specific DNA binding protein 2, 48kDa

Calculated molecular weight:
48 kDa

Observed molecular weight:
55-60 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol

DDB p48 subunit, DDB2, DDBB, DNA damage binding protein 2, UV DDB 2, UV DDB2

DDB2, also named as DNA damage-binding protein 2 or UV-damaged DNA-binding protein 2, is a 427 amino acid protein, which contains seven WD repeats and belongs to the WD repeat DDB2/WDR76 family. DDB2 is ubiquitously expressed, with highest levels in corneal endothelium and lowest levels in brain. DDB2 localizes in the nucleus and is required for DNA repair. DDB2 regulates negatively the constitutive expression of the SOD2 gene in breast cancer cells and exerts, at least in part, a control of breast cacner cell growth. DDB2 can play a role as oncogene and may become a promising candidate as a predictive marker in breast cancer.

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