DNASE2 Antibody 0 Publications

Rabbit Polyclonal| Catalog number: 15934-1-AP

  • Print page
  • Download PDF

Be the first to review this product



Con: 20 μg/150 μl

Choose size:

Please visit your regions distributor:

Species specificity:
human, mouse, rat

Positive WB detected in:
HeLa cells

Positive IP detected in:
HeLa cells

Recommended dilution:
WB : 1:200-1:1000
IP : 0.5-4.0 ug for IP and 1:200-1:1000 for WB

Product Information


Purification method:
Antigen affinity purification


PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information

Full name:
deoxyribonuclease II, lysosomal

Calculated molecular weight:
360aa,40 kDa

Observed molecular weight:
34 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol

Acid DNase, Deoxyribonuclease 2 alpha, Deoxyribonuclease II alpha, DNase II alpha, DNASE2, DNASE2A, DNL, DNL2, Lysosomal DNase II, R31240_2

DNASE2, or 'acid DNase,' hydrolyzes DNA under acidic conditions and is one of 2 distinct mammalian DNases. It hydrolyzes DNA under acidic conditions with a preference for double-stranded DNA. It has a key role in the degradation of nuclear DNA in cellular apoptosis during development [PMID:18812394]. Besieds, it is necessary for proper fetal development and for definitive erythropoiesis in fetal liver, where it degrades nuclear DNA expelled from erythroid precursor cells. It has been demonstrated to be responsible forDNA degradation in apoptotic cells engulfed by macrophages and exogenous DNA on the skin surface [PMID:23019102]. DNASE2 exists some isoforms with MV 39 and 34 kDa. (PMID: 14644493)

to top