DYNLT1 Antibody 4 Publications

Rabbit Polyclonal| Catalog number: 11954-1-AP

Featured Product KD/KO validated

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Freight/Packing

Con: 61 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
human brain tissue, human heart tissue, Sp2/0 cells

Positive IP detected in:
mouse skeletal muscle tissue

Positive IHC detected in:
human pancreas tissue

Positive IF detected in:
HepG2 cells

Recommended dilution:
WB : 1:500-1:1000
IP : 0.5-4.0 ug for IP and 1:200-1:1000 for WB
IHC : 1:20-1:200
IF : 1:50-1:500

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
dynein, light chain, Tctex-type 1

Calculated molecular weight:
113aa,12 kDa

Observed molecular weight:
12 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
DYNLT1

Synonyms
CW 1, DYNLT1, Protein CW 1, TCTEL1, tctex 1, TCTEX1
Background

DYNLT (or Tctex-1) was originally described as a light chain component of the dynein motor complex. Tctex-1 also has several dynein-independent functions, including roles in G protein signaling activation and neuronal growth. Tctex-1 is selectively enriched in proliferating neural progenitors of both embryonic and adult brains. Genetic knockdown of Tctex-1 in radial precursors promoted neurogenesis, indicating its implication in regulation of cortical neurogenesis. (Pubmed: 19448628)


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