ECE2 Antibody 1 Publications

Rabbit Polyclonal| Catalog number: 15418-1-AP

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Freight/Packing

Con: 40 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
mouse liver tissue, mouse lung tissue, mouse ovary tissue

Positive IP detected in:
mouse liver tissue

Positive IHC detected in:
human liver tissue

Recommended dilution:
WB : 1:500-1:1000
IP : 0.5-4.0 ug for IP and 1:500-1:1000 for WB
IHC : 1:100-1:400

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
endothelin converting enzyme 2

Calculated molecular weight:
100 kDa

Observed molecular weight:
100 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
ECE2

Synonyms
ECE2, endothelin converting enzyme 2, KIAA0604
Background

Endothelin-converting enzymes (ECEs) are the key enzymes in the endothelin (ET) biosynthesis that catalyze the conversion of big ET, the biologically inactive precursor of mature ET. Two enzymes, termed ECE-1 and ECE-2, have been molecularly identified. ECE2(Endothelin-converting enzyme 2) is also named as KIAA0604 and belongs to the methyltransferase superfamily in the N-terminal section, belongs to the peptidase M13 family in the C-terminal section. It is able to process endoproteolytically peptides intermediates to generate biologically active peptides.


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