EED Antibody 3 Publications

Rabbit Polyclonal| Catalog number: 16818-1-AP

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Freight/Packing

Con: 20 μg/150 μl

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Species specificity:
human

Positive WB detected in:
COLO 320 cells, A431 cells, COLO 320 cells, HeLa cells, HepG2 cells, K-562 cells, PC-3 cells

Positive IP detected in:
PC-3 cells

Positive IHC detected in:
human tonsillitis tissue

Positive IF detected in:
HepG2 cells, HeLa cells

Recommended dilution:
WB : 1:500-1:2000
IP : 0.5-4.0 ug for IP and 1:500-1:1000 for WB
IHC : 1:50-1:500
IF : 1:50-1:500

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
embryonic ectoderm development

Calculated molecular weight:
466aa,53 kDa

Observed molecular weight:
53 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
EED

Synonyms
EED, embryonic ectoderm development, HEED, Polycomb protein EED, WAIT 1, WAIT1
Background

EED is a member of the Polycomb-group (PcG) family. PcG family members form multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes over successive cell generations. This protein interacts with enhancer of zeste 2, the cytoplasmic tail of integrin beta7, immunodeficiency virus type 1 (HIV-1) MA protein, and histone deacetylase proteins. This protein mediates repression of gene activity through histone deacetylation, and may act as a specific regulator of integrin function. EED has three isoforms, with the molecular weight of isoforms 1/2/3: 50/53/46 kDa.


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