EIF4A2 Antibody 0 Publications

Rabbit Polyclonal| Catalog number: 11280-1-AP

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Freight/Packing

Con: 20 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
Jurkat cells, Jurkat cells, mouse ovary tissue, Raji cells

Positive IP detected in:
Jurkat cells

Positive IHC detected in:
human ovary tumor tissue, human gliomas tissue, human ovary tumor tissue

Recommended dilution:
WB : 1:200-1:1000
IP : 0.5-4.0 ug for IP and 1:500-1:1000 for WB
IHC : 1:20-1:200

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
eukaryotic translation initiation factor 4A, isoform 2

Calculated molecular weight:
47 kDa

Observed molecular weight:
47kd

GenBank accession number:

Gene ID (NCBI):

Gene symbol
EIF4A2

Synonyms
BM 010, DDX2B, eIF 4A II, EIF4A, eIF4A II, EIF4A2, EIF4F
Background

Eukaryotic initiation factor 4A (EIF4A) has an essential role in the binding of mRNA to the 43S preinitiation complex when protein synthesis begins, as EIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon. EIF4A2 is a ATP-dependent RNA helicase, which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome.


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