Important Customer Notice Regarding Covid-19 Outbreak. Read more.

Back

Endoglin/CD105 Antibody 0 Publications

Rabbit Polyclonal| Catalog number: 18471-1-AP

Be the first to review this product

-_-

Freight/Packing

Con: 45 μg/150 μl

Choose size:

Please visit your regions distributor:

Request quote for
bulk/custom formulations

Special offer: Add control/tag antibody for $99
Load more

Tested Applications

Applications:
ELISA
Application not tested? Please see our Guarantee


Species specificity:
human, mouse, rat
Recommended dilution:
Sample-dependent, check data in Validation tab

Product Information

Source:
Rabbit
Purification method:
Antigen affinity purification
Isotype:
IgG
Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information

Immunogen:
Endoglin/CD105 fusion protein Ag13335
Full name:
endoglin
Calculated molecular weight:
71 kDa
Observed molecular weight:
GenBank accession number:
BC014271
Gene ID (NCBI):
2022
Gene symbol
ENG
Synonyms
CD105, END, Endoglin, ENG, HHT1, ORW, ORW1

Background

Endoglin (ENG, CD105) is a homodimeric cell membrane glycoprotein of 180 kDa, composed of disulphide-linked subunits of 95 kDa. Endoglin is a proliferation-associated and hypoxia-inducible protein mainly expressed on vascular endothelial cells. It acts as an accessory receptor for transforming growth factor beta (TFG-β) and is involved in vascular development and remodelling. The important role of Endoglin in angiogenesis and in tumor progression makes it an ideal target for antiangiogenic therapy and a good marker for tumor prognosis. (PMID: 1326540; 14528280; 21737653; 12773481)


Back
to top