FADD Antibody 3 Publications

Rabbit Polyclonal| Catalog number: 14906-1-AP

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Freight/Packing

Con: 20 μg/150 μl

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Species specificity:
human, mouse, rat, monkey, sheep

Positive WB detected in:
HT-1080 cells, HT-1080 cells, mouse pancreas tissue

Positive IP detected in:
A549 cells

Positive IHC detected in:
human lung cancer tissue

Positive IF detected in:
HT-1080 cells

Recommended dilution:
WB : 1:200-1:1000
IP : 0.5-4.0 ug for IP and 1:200-1:1000 for WB
IHC : 1:20-1:200
IF : 1:20-1:200

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
Fas (TNFRSF6)-associated via death domain

Calculated molecular weight:
23 kDa

Observed molecular weight:
23 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
FADD

Synonyms
FADD, GIG3, MORT1, Protein FADD
Background

Fas-Associated protein with Death Domain (FADD), also called MORT1 or GIG3, is encoded by the FADD gene. FADD is an adaptor protein that bridges members of the tumor necrosis factor receptor superfamily, such as the Fas-receptor, to procaspases 8 and 10 to form the death-inducing signaling complex (DISC) during apoptosis. As well as its most well known role in apoptosis, FADD has also been seen to play a role in other processes including proliferation, cell cycle regulation and development.


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