Fc Epsilon RI Alpha Polyclonal antibody

Fc Epsilon RI Alpha Polyclonal Antibody for WB,ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse

Applications

WB, IHC, IF,ELISA

Conjugate

Unconjugated

Cat no : 10980-1-AP

Synonyms

Fc epsilon RI alpha, FCE1A, FCER1A, FcERI, FceRIa, IgE Fc receptor subunit alpha



Tested Applications

Positive WB detected inhuman spleen tissue, PC-3 cells, RAW 264.7 cells

Recommended dilution

ApplicationDilution
Western Blot (WB)WB : 1:500-1:1000
Sample-dependent, check data in validation data gallery

Product Information

10980-1-AP targets Fc Epsilon RI Alpha in WB, IHC, IF,ELISA applications and shows reactivity with human, mouse samples.

Tested Reactivity human, mouse
Cited Reactivity human, mouse
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen Fc Epsilon RI Alpha fusion protein Ag1398
Full Name Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide
Calculated molecular weight 30 kDa
Observed molecular weight 55 kDa
GenBank accession numberBC015195
Gene symbol FCER1A
Gene ID (NCBI) 2205
Conjugate Unconjugated
Form Liquid
Purification Method Antigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Background Information

Fc fragment of IgE, high affinity I, receptor for, alpha polypeptide, also known as high affinity immunoglobulin epsilon receptor subunit alpha, FCER1A and FCE1A, is a single-pass type I membrane protein which contains 2 immunoglobulin-like domains. FCER1A is a subunit of the IgE receptor, which is composed of one glycosylated alpha (FCER1A), one beta (FCER1B), and two gamma (FCER1G) subunits. The high affinity IgE receptor plays a central role in allergic disease, coupling allergen and mast cell to initiate the inflammatory and immediate hypersensitivity responses that are characteristic of disorders such as hay fever and asthma.

Protocols

Product Specific Protocols
WB protocol for Fc Epsilon RI Alpha antibody 10980-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

Publications

SpeciesApplicationTitle
humanIHC

Allergy

Alveolar mast cells shift to an FcεRI-expressing phenotype in mild atopic asthma: a novel feature in allergic asthma pathology.

Authors - Andersson C K CK
humanIHC

Thorax

Novel site-specific mast cell subpopulations in the human lung.

Authors - Andersson C K CK
humanIHC

J Allergy Clin Immunol

Mast cell-associated alveolar inflammation in patients with atopic uncontrolled asthma.

Authors - Andersson Cecilia K CK
mouseIF

Science

Response to Comment on "Tumor-initiating cells establish an IL-33-TGF-β niche signaling loop to promote cancer progression".

Authors - Sachiko Taniguchi