FMRP Antibody 0 Publications

Rabbit Polyclonal| Catalog number: 13755-1-AP

Featured Product KD/KO validated

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Freight/Packing

Con: 36 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
K-562 cells, Jurkat cells

Positive IP detected in:
HeLa cells

Positive IHC detected in:
human gliomas tissue

Positive IF detected in:
HepG2 cells, Hela cells, HepG2 cells

Recommended dilution:
WB : 1:500-1:3000
IP : 0.5-4.0 ug for IP and 1:500-1:2000 for WB
IHC : 1:20-1:200
IF : 1:50-1:500

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
fragile X mental retardation 1

Calculated molecular weight:
632aa,71 kDa

Observed molecular weight:
59-72 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
FMR1

Synonyms
FMR1, FMRP, fragile X mental retardation 1, FRAXA, POF, POF1, Protein FMR 1
Background

The selective RNA-binding protein FMRP forms a messenger ribonucleoprotein complex that associates with polyribosomes, implicating in regulation of translation. FMR1 is a component of the CYFIP1-EIF4E-FMR1 complex which binds to and reperss the mRNA. It also has a role in the transport of mRNA from the nucleus to the cytoplasm. FMR1 exists several isforms and the molecular weight of FMR1 is about 59-72 kDa.


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