FOXP1 Antibody 0 Publications

Rabbit Polyclonal| Catalog number: 18596-1-AP

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Con: 32 μg/150 μl

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Tested Applications

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Species specificity:
human, mouse, rat

Recommended dilution:

Product Information


Purification method:
Antigen affinity purification


PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information

Full name:
forkhead box P1

Calculated molecular weight:
114aa,12 kDa

Observed molecular weight:

GenBank accession number:

Gene ID (NCBI):

Gene symbol

12CC4, forkhead box P1, Forkhead box protein P1, FOXP1, hFKH1B, HSPC215, QRF1

FOXP1, also named as HSPC215, is a transcriptional repressor that plays an important role in the specification and differentiation of lung epithelium. It is essential transcriptional regulator of B cell developmen. A chromosomal aberration involving FOXP1 is found in acute lymphoblastic leukemia. FOXP1 is implicated in the pathogenesis of DLBCL and MALT lymphomas, through the identification of recurrent chromosome translocations that upregulate its expression levels and the correlation between high-level FOXP1 expression and poor prognosis. On initial examination, these data seem contrary to findings from the study of FOXP1 in epithelial malignancies, which suggest that it may represent a tumor suppressor gene. Convincing evidence linking the loss of the FOXP1 N-terminus and malignancy has already been generated through the study of recurrent viral integration sites that generate avian nephroblastomas.(PMID:18077790) The antibody recognize 2 smaller 60-65kd isoforms in mouse Lung.

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