FURIN Antibody 0 Publications

Rabbit Polyclonal| Catalog number: 18413-1-AP

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Freight/Packing

Con: 65 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
HeLa cells, COLO 320 cells, HeLa cells

Positive IP detected in:
HeLa cells

Positive IHC detected in:
human placenta tissue

Recommended dilution:
WB : 1:500-1:1000
IP : 0.5-4.0 ug for IP and 1:500-1:1000 for WB
IHC : 1:20-1:200

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
furin (paired basic amino acid cleaving enzyme)

Calculated molecular weight:
87 kDa

Observed molecular weight:
90 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
FURIN

Synonyms
Dibasic processing enzyme, FUR, FURIN, PACE, PCSK3, SPC1
Background

FURIN, also named as FUR, PACE, PCSK3, SPC1, Kex2p, is likely to represent the ubiquitous endoprotease activity within constitutive secretory pathways and capable of cleavage at the RX(K/R)R consensus motif. Furin is synthesized as an inactive zymogen that may minimize the occurrence of premature enzymatic activity that would lead to alternative protein activation or degradation. Glycosylation and other post-translational modifications can make the pre-pro furin run at 100-110 kDa, the mature furin at 98-95 kDa and shed furin at 90 kDa.


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