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Dysadherin Antibody 0 Publications

Rabbit Polyclonal| Catalog number: 12166-1-AP

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Con: 20 μg/150 μl

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Tested Applications

Applications:
WB, IHC, ELISA
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Images See all

Dysadherin Antibody WB mouse small intestine tissue 12166-1-AP

mouse small intestine tissue were subjected to SDS PAGE followed by western blot with 12166-1-AP(Dysadherin antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours

Dysadherin Antibody IHC human kidney tissue 12166-1-AP

Immunohistochemical of paraffin-embedded human kidney using 12166-1-AP(Dysadherin antibody) at dilution of 1:50 (under 10x lens)

Dysadherin Antibody IHC human kidney tissue 12166-1-AP

Immunohistochemical of paraffin-embedded human kidney using 12166-1-AP(Dysadherin antibody) at dilution of 1:50 (under 40x lens)

Species specificity:
human, mouse
Positive WB detected in:
mouse small intestine tissue, human placenta tissue
Positive IHC detected in:
human kidney tissue, human cervical cancer tissue
Recommended dilution:
WB : 1:500-1:2400
IHC : 1:20-1:200

Protocols

Product-specific protocols

Standard Protocols

Product Information

Source:
Rabbit
Purification method:
Antigen affinity purification
Isotype:
IgG
Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information

Immunogen:
Dysadherin fusion protein Ag2808
Full name:
FXYD domain containing ion transport regulator 5
Calculated molecular weight:
178aa,19 kDa
Observed molecular weight:
24 kDa
GenBank accession number:
BC009642
Gene ID (NCBI):
53827
Gene symbol
FXYD5
Synonyms
dysad, Dysadherin, FXYD5, HSPC113, IWU 1, IWU1, KCT1, OIT2, PRO6241, RIC, UNQ2561/PRO6241

Background

Dysadherin, also known as FXYD5 (FXYD domain containing ion transport regulator 5), is a cancer-associated cell membrane glycoprotein which belongs to the FXYD family. The FXYD family, which contains seven members, are tissue specific regulators of the Na,K-ATPase. Dysadherin is involved in down-regulation of E-cadherin, which plays important roles in tumor development and metastasis. It is present in spleen, lung, skeletal muscle, and testis. Increased expression of dysadherin has been associated with increased cell motility and metastatic potential.


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