Dysadherin Antibody 0 Publications

Rabbit Polyclonal| Catalog number: 12166-1-AP

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Freight/Packing

Con: 20 μg/150 μl

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Species specificity:
human, mouse

Positive WB detected in:
mouse small intestine tissue, human placenta tissue

Positive IHC detected in:
human kidney tissue, human cervical cancer tissue, human kidney tissue

Recommended dilution:
WB : 1:500-1:2400
IHC : 1:20-1:200

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
FXYD domain containing ion transport regulator 5

Calculated molecular weight:
178aa,19 kDa

Observed molecular weight:
24 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
FXYD5

Synonyms
dysad, Dysadherin, FXYD5, HSPC113, IWU 1, IWU1, KCT1, OIT2, PRO6241, RIC, UNQ2561/PRO6241
Background

Dysadherin, also known as FXYD5 (FXYD domain containing ion transport regulator 5), is a cancer-associated cell membrane glycoprotein which belongs to the FXYD family. The FXYD family, which contains seven members, are tissue specific regulators of the Na,K-ATPase. Dysadherin is involved in down-regulation of E-cadherin, which plays important roles in tumor development and metastasis. It is present in spleen, lung, skeletal muscle, and testis. Increased expression of dysadherin has been associated with increased cell motility and metastatic potential.


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