GABRR1 Antibody 0 Publications

Rabbit Polyclonal| Catalog number: 25899-1-AP

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Freight/Packing

Con: 40 μg/150 μl

Choose size:

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Species specificity:
human, mouse

Positive WB detected in:
mouse brain tissue, mouse skeletal muscle tissue

Recommended dilution:
WB : 1:500-1:1000

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
gamma-aminobutyric acid (GABA) receptor, rho 1

Calculated molecular weight:
479aa, 56 kDa

Observed molecular weight:
50-56 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
GABRR1

Synonyms
GABA(A) receptor subunit rho 1, GABA(C) receptor, GABRR1
Background

GABRR1 is a member of a family of ligand-gated chloride channels that are the major inhibitory neurotransmitter receptors in the central nervous system. GABRR1 acts as a rho-1 receptor of GABA, the major inhibitory neurotransmitter in the vertebrate brain, may play a role in retinal neurotransmission. And then, GABRR1 is highly expressed in the retina and in a lesser extent in brain, lung and thymus. There are 3 isoforms for GABRR1 produced by alternative splicing, with the molecular weights of 46 kDa, 53 kDa, 56 kDa, respectively.


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