GAMT Antibody 1 Publications

Rabbit Polyclonal| Catalog number: 10880-1-AP

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Freight/Packing

Con: 43 μg/150 μl

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Species specificity:
human, mouse, rat, zebrafish

Positive WB detected in:
mouse liver tissue, HEK-293 cells, human brain tissue, human heart tissue, mouse brain tissue, mouse liver tissue, rat liver tissue

Positive IHC detected in:
human prostate cancer tissue, human liver tissue, human prostate cancer tissue

Recommended dilution:
WB : 1:500-1:2000
IHC : 1:10-1:100

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
guanidinoacetate N-methyltransferase

Calculated molecular weight:
26 kDa

Observed molecular weight:
26 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
GAMT

Synonyms
GAMT, PIG2, TP53I2
Background

GAMT converts the latter to creatine with S-adenosylmethionine as the methyl donor. GAMT was induced in human and mouse cells in response to genotoxic and metabolic stress. GAMT was required for p53-dependent upregulation of creatine biosynthesis, fatty acid oxidation, and apoptosis in response to glucose deprivation.


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