GAR1 Antibody 3 Publications

Rabbit Polyclonal| Catalog number: 11711-1-AP

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Freight/Packing

Con: 49 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
A375 cells, human skin tissue

Positive IP detected in:
A375 cells

Positive IHC detected in:
human skin cancer tissue

Positive IF detected in:
HepG2 cells

Recommended dilution:
WB : 1:500-1:1000
IP : 0.5-4.0 ug for IP and 1:200-1:1000 for WB
IHC : 1:20-1:200
IF : 1:10-1:100

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
GAR1 ribonucleoprotein homolog (yeast)

Calculated molecular weight:
217aa,22 kDa

Observed molecular weight:
28kd

GenBank accession number:

Gene ID (NCBI):

Gene symbol
GAR1

Synonyms
GAR1, NOLA1, snoRNP protein GAR1
Background

GAR1, other named NOLA1, is a subunit of H/ACA and telomerase. Thought is not required for H/ACA protein assembly, GAR1 is necessary for ribosome biogenesis and telomere. H/ACA involves in class specify the sites of uridine-to-pseudouridine. It contains a core domain that flanked by glycine- and arginine-rich(GAR) domains. GAR1 also required for correct processing or intranuclear trafficking of TERC, the RNA component of the telomerase reverse transciptase(TERT) holoenzyme.


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