GARS Antibody 1 Publications

Rabbit Polyclonal| Catalog number: 15831-1-AP

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Freight/Packing

Con: 28 μg/150 μl

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Species specificity:
human, mouse, rat, Drosophila

Positive WB detected in:
human brain tissue,human liver tissue, human testis tissue, HeLa cells, HepG2 cells, HT-1080 cells

Positive IP detected in:
mouse liver tissue

Positive IHC detected in:
human skin cancer tissue

Positive IF detected in:
HepG2 cells

Recommended dilution:
WB : 1:500-1:2000
IP : 0.5-4.0 ug for IP and 1:500-1:1000 for WB
IHC : 1:20-1:200
IF : 1:10-1:100

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
glycyl-tRNA synthetase

Calculated molecular weight:
739aa,83 kDa

Observed molecular weight:
75-80 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
GARS

Synonyms
AP 4 A synthetase, CMT2D, DSMAV, GARS, Glycine tRNA ligase, glycyl tRNA synthetase, GlyRS, HMN5, SMAD1
Background

GARS(glycinamide ribonucleotide synthetase) perform an essential function in protein synthesis by catalyzing the esterification of an amino acid to its cognate tRNA.GARS, however, is a ubiquitously expressed α2 homodimer responsible for charging tRNA molecules with glycine, this enzyme is essential for protein synthesis in all cells and tissues(PMID:17035524 ).It can exist as a oligomer with 250KDa(PMID:22504945).


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