GOT1 Antibody 3 Publications

Rabbit Polyclonal| Catalog number: 14886-1-AP

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Freight/Packing

Con: 73 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
mouse brain tissue, HepG2 cells, human brain tissue, human heart tissue, human skeletal muscle tissue, L02 cells, mouse heart tissue, mouse liver tissue, mouse skeletal muscle tissue, rat brain tissue

Positive IP detected in:
mouse brain tissue

Positive IF detected in:
L02 cells

Recommended dilution:
WB : 1:500-1:2000
IP : 0.5-4.0 ug for IP and 1:500-1:2000 for WB
IF : 1:50-1:500

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
glutamic-oxaloacetic transaminase 1, soluble (aspartate aminotransferase 1)

Calculated molecular weight:
46 kDa

Observed molecular weight:
43-46 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
GOT1

Synonyms
AATC, CAT, GIG18, GOT1, Transaminase A
Background

Glutamate oxaloacetate transaminase 1 (GOT1) catalyzes the reversible reaction of L-aspartate and alpha-ketoglutarate into oxaloacetate and L-glutamate and plays a key role in carbon and nitrogen metabolism. GOT1 can potentially control the intracellular levels of reactive oxygen species (ROS) through NADPH synthesis and enhances tumor growth. GOT1 expression correlates with the growth of several tumors.


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