GPNMB Antibody 2 Publications

Rabbit Polyclonal| Catalog number: 20338-1-AP

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Freight/Packing

Con: 20 μg/150 μl

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Species specificity:
human, mouse

Positive WB detected in:
mouse liver tissue, A375 cells, Transfected HEK-293 cells

Positive IHC detected in:
human liver cancer tissue, human liver cancer tissue, human renal cell carcinoma tissue

Recommended dilution:
WB : 1:500-1:1000
IHC : 1:20-1:200

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
glycoprotein (transmembrane) nmb

Calculated molecular weight:
64 kDa

Observed molecular weight:
68 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
GPNMB

Synonyms
GPNMB, HGFIN, Transmembrane glycoprotein NMB
Background

GPNMB also known as HGFIN, osteoactivin, and DC-HIL, is a type I membrane glycoprotein involved in various biological processes, including inflammation, invasion and metastasis of malignant tumors, cell differentiation, and tissue regeneration. GPNMB shows expression in the lowly metastatic human melanoma cell lines and xenografts but does not show expression in the highly metastatic cell lines. GPNMB acts as an osteogenic factor that stimulates osteoblast differentiation in vivo and in vitro.


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