HEY1 Antibody 9 Publications

Rabbit Polyclonal| Catalog number: 19929-1-AP

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Freight/Packing

Con: 47 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
DU 145 cells, mouse testis tissue

Positive IP detected in:
mouse kidney tissue

Positive IHC detected in:
human brain tissue, human brain tissue, human kidney tissue

Recommended dilution:
WB : 1:500-1:2000
IP : 0.5-4.0 ug for IP and 1:500-1:1000 for WB
IHC : 1:20-1:200

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
hairy/enhancer-of-split related with YRPW motif 1

Calculated molecular weight:
304aa,33 kDa

Observed molecular weight:
32-34 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
HEY1

Synonyms
BHLHb31, CHF 2, CHF2, HERP2, HESR 1, HESR1, HEY1, hHRT1, HRT 1, HRT1, OAF1
Background

Hairy/enhancer of split-related proteins are basic helix-loop-helix (bHLH) transcription factors implicated in cell fate decision and boundary formation. And HEY1 is one of such protein. It is the direct downstream effector of Notch signaling which may be required for cardiovascular development. It preferentially bind to the canonical E box sequence 5'-CACGTG-3' and acts as a transcriptional repressor. HEY1 is a 33kDa protein and forms dimer by self-associating.


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