HLA-DMA Antibody 0 Publications

Rabbit Polyclonal| Catalog number: 11838-1-AP

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Freight/Packing

Con: 20 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
rat spleen tissue, human liver tissue

Recommended dilution:
WB : 1:500-1:1000

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
major histocompatibility complex, class II, DM alpha

Calculated molecular weight:
261aa,29 kDa

Observed molecular weight:
55-60 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
HLA-DMA

Synonyms
D6S222E, DAMA 147C13.1 001, DAMC 226H3.5 001, DAQB 96B10.1 001, DASS 67H14.8 001, DMA, DMA protein, hCG_2001572, HLA DMA, HLA DMA protein, HLADM, HLA-DMA, RING6, XXbac BCX136A3.1 001, XXbac BPG181M17.3 001
Background

HLA-DMA and -DMB form a functional heterodimer that is critical in the pathway of class II antigen presentation. HLA-DM plays a critical role in catalyzing the release of Class II HLA-associated invariant chain-derived peptides (CLIP) from newly synthesized class II HLA molecules and freeing the peptide binding site for acquisition of antigenic peptides. This antibody recognize the 33kd HLA-DMA and the 50-60kd dimer in Western blotting.


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