HSPA2 Antibody 4 Publications

Rabbit Polyclonal| Catalog number: 12797-1-AP

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Freight/Packing

Con: 21 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
human ileum tissue, A431 cells, HeLa cells, human brain tissue, human kidney tissue, human skeletal muscle tissue, MCF-7 cells

Positive IP detected in:
mouse skeletal muscle tissue

Positive IHC detected in:
human testis tissue,human prostate hyperplasia tissue, human ovary tumor tissue, mouse ovary tissue

Positive FC detected in:
HeLa cells

ApplicationNote:
It works very well. By Dr. Fengyun Sun

Recommended dilution:
WB : 1:500-1:2000
IP : 0.5-4.0 ug for IP and 1:500-1:2000 for WB
IHC : 1:20-1:200

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
heat shock 70kDa protein 2

Calculated molecular weight:
639aa,70 kDa

Observed molecular weight:
65-70 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
HSPA2

Synonyms
Heat shock 70 kDa protein 2, heat shock 70kDa protein 2, HSP70 2, HSP70 3, HSPA2
Background

Human HSPA2 is a member of the HSPA (HSP70) family of heat-shock proteins, encoded by the gene originally described as testis-specific. Recently, it has been reported that HSPA2 can be also expressed in human somatic tissues in a cell-type specific manner. HSPA2 is a cytosol/nuclear protein able to translocate between cytoplasm and nucleus. HSPA2 is involved in sperm maturity, function and fertility. Aberrant expression of HSPA2 in testes has been connected with male infertility. Recently, HSPA2 has attracted increased interest due to its possible involvement in carcinogenesis of non-testicular tissues. This antibody well recognized the endogenous HSPA4 protein in testis and multiple cell lines. (21373891)


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