HSP27 Antibody 11 Publications

Rabbit Polyclonal| Catalog number: 18284-1-AP

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Freight/Packing

Con: 62 μg/150 μl

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Species specificity:
human, rat, mouse

Positive WB detected in:
HeLa cells, C6 cells, human skeletal muscle tissue, human stomach tissue, MCF-7 cells, mouse liver tissue

Positive IHC detected in:
human lung cancer tissue, human liver cancer tissue

Positive IF detected in:
MCF-7 cells, Hela cells

Recommended dilution:
WB : 1:500-1:3000
IHC : 1:50-1:500
IF : 1:10-1:100

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
heat shock 27kDa protein 1

Calculated molecular weight:
19-23 kDa

Observed molecular weight:
24-27 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
HSPB1

Synonyms
Heat shock protein beta 1, HSP 27, Hsp25, HSP27, HSP28, HSPB1
Background

HSPB1, also known as heat shock protein 27 (Hsp27), belongs to the small heat shock protein family which is induced in response to environmental challenges or/and developmental transitions. It is also an anti-apoptotic protein that plays crucial roles in tumorigenesis and cell survival and is reported to be an independent prognosis marker for cancer. Recently HSPB1 has been found to be a valuable marker for melanoma. In addition to the predicted 27 kDa, an extra 50-55 kDa representing dimeric form of HSPB1 may also be observed (21353161) . It's notable that mouse HSP27 is also named HSP25 and has the predicted MW between 19-23 kDa.


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