ICAM-1 Antibody 20 Publications

Rabbit Polyclonal| Catalog number: 10831-1-AP

Featured Product KD/KO validated

  • Print page
  • Download PDF

Be the first to review this product


-_-

Freight/Packing

Con: 51 μg/150 μl

Choose size:

Please visit your regions distributor:


Species specificity:
human, mouse, bovine, rat

Positive WB detected in:
L02 cells,Raji cells, mouse liver tissue

Positive IP detected in:
Raji cells

Positive IHC detected in:
human lung cancer tissue, human liver cancer tissue, human tonsillitis tissue

Positive IF detected in:
human lung cancer tissue

Positive FC detected in:
Raji cells

Recommended dilution:
WB : 1:500-1:1000
IP : 0.5-4.0 ug for IP and 1:500-1:2000 for WB
IHC : 1:50-1:200
IF : 1:50-1:500

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
intercellular adhesion molecule 1

Calculated molecular weight:
90 kDa

Observed molecular weight:
85-95 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
ICAM1

Synonyms
BB2, CD54, ICAM 1, ICAM1, P3.58
Background

ICAM-1 (CD54) is a 90-kDa transmembrane glycoprotein of the immunoglobulin superfamily and is critical for the firm attachment and transmigration of leukocytes out of blood vessels and into tissues (PMID: 19307690). ICAM-1 is expressed by several cell types, typically on endothelial cells and cells of the immune system, and its expression can be up-regulated by various stimuli, including TNF-α, INF-γ, IL-1 and thrombin (PMID: 3086451; 9694714; 15979056). It is a ligand for LFA-1 and Mac-1, serves as a receptor for rhinovirus, and is one of several receptors used by Plasmodium falciparum (PMID: 2566624; 2538244; 2475784).


Back
to top