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Interferon gamma Antibody 29 Publications

Rabbit Polyclonal| Catalog number: 15365-1-AP

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Freight/Packing

Con: 38 μg/150 μl

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Tested Applications

Applications:
IHC, IF, ELISA
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Species specificity:
human, rat
Recommended dilution:
Sample-dependent, check data in Validation tab

Product Information

Source:
Rabbit
Purification method:
Antigen affinity purification
Isotype:
IgG
Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC.Aliquoting is unnecessary for -20oC storage.

Immunogen Information

Immunogen:
Interferon gamma fusion protein Ag8321
Full name:
interferon, gamma
Calculated molecular weight:
166aa,19 kDa
Observed molecular weight:
GenBank accession number:
BC070256
Gene ID (NCBI):
3458
Gene symbol
IFNG
Synonyms
IFG, IFI, IFN gamma, IFNG, IFN-γ, Immune interferon, Interferon gamma, interferon, gamma

Background

Interferon gamma (IFNG) is a soluble cytokine that is the only member of the type II class of interferons. It is secreted by Th1 cells, cytotoxic T cells and NK cells. The cytokine is associated with antiviral, immunoregulatory and anti-tumor properties and is a potent activator of macrophages. It plays crucial roles in pathogen clearance. Aberrant IFNG expression is associated with a number of autoinflammatory and autoimmune diseases. It has been identified in many studies as a biomarker for pleural tuberculosis (TB). Mutations in this gene are associated with aplastic anemia.


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