IFN Gamma Polyclonal antibody
IFN Gamma Polyclonal Antibody for WB, ELISA
Host / Isotype
Rabbit / IgG
Reactivity
human and More (1)
Applications
WB, IHC, IF,ELISA
Conjugate
Unconjugated
Cat no : 15365-1-AP
Synonyms
Validation Data Gallery
Tested Applications
Positive WB detected in | Recombinant protein protein |
Recommended dilution
Application | Dilution |
---|---|
Western Blot (WB) | WB : 1:2000-1:12000 |
Sample-dependent, check data in validation data gallery |
Published Applications
KD/KO | See 1 publications below |
WB | See 19 publications below |
IHC | See 14 publications below |
IF | See 7 publications below |
Product Information
15365-1-AP targets IFN Gamma in WB, IHC, IF,ELISA applications and shows reactivity with human samples.
Tested Reactivity | human |
Cited Reactivity | human, rat |
Host / Isotype | Rabbit / IgG |
Class | Polyclonal |
Type | Antibody |
Immunogen | IFN Gamma fusion protein Ag8321 |
Full Name | IFN gamma |
Calculated molecular weight | 166 aa, 19 kDa |
GenBank accession number | BC070256 |
Gene symbol | IFNG |
Gene ID (NCBI) | 3458 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Antigen affinity purification |
Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
Background Information
IFN gamma (IFNG) is a soluble cytokine that is the only member of the type II class of IFN. It is secreted by Th1 cells, cytotoxic T cells and NK cells. The cytokine is associated with antiviral, immunoregulatory and anti-tumor properties and is a potent activator of macrophages. It plays crucial roles in pathogen clearance. Aberrant IFNG expression is associated with a number of autoinflammatory and autoimmune diseases. It has been identified in many studies as a biomarker for pleural tuberculosis (TB). Mutations in this gene are associated with aplastic anemia.
Protocols
Product Specific Protocols | |
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WB protocol for IFN Gamma antibody 15365-1-AP | Download protocol |
Standard Protocols | |
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Click here to view our Standard Protocols |
Publications
Species | Application | Title |
---|---|---|
J Cell Physiol Dehydroepiandrosterone stimulates inflammation and impairs ovarian functions of polycystic ovary syndrome. | ||
Am J Chin Med Total Glycosides of Peony Protects Against Inflammatory Bowel Disease by Regulating IL-23/IL-17 Axis and Th17/Treg Balance. | ||
Cancer Res Low-dose IFN-γ induces tumor cell stemness in the tumor microenvironment of non-small cell lung cancer. | ||
Mol Genet Genomics A comparison of CRISPR/Cas9 and siRNA-mediated ALDH2 gene silencing in human cell lines. | ||
Transplantation Decreased percentages of regulatory T cells are necessary to activate Th1-th17-th22 responses during acute rejection of the peripheral nerve xenotransplantation in mice. | ||
J Huazhong Univ Sci Technolog Med Sci Implications of Th1 and Th17 cells in pathogenesis of oral lichen planus. |