IGFBP3 Antibody 3 Publications

Rabbit Polyclonal| Catalog number: 10189-2-AP

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Freight/Packing

Con: 37 μg/150 μl

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Species specificity:
human, mouse, chicken, rat

Positive WB detected in:
A2780 cells,HeLa cells

Positive IHC detected in:
human breast cancer tissue, human breast cancer tissue, human colon cancer tissue

Positive IF detected in:
HeLa cells

Recommended dilution:
WB : 1:200-1:500
IHC : 1:20-1:200
IF : 1:10-1:100

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
insulin-like growth factor binding protein 3

Calculated molecular weight:
32 kDa

Observed molecular weight:
32 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
IGFBP3

Synonyms
BP 53, IBP 3, IBP3, IGF binding protein 3, IGFBP 3, IGFBP3
Background

Insulin-like growth factor binding protein-3 (IGFBP-3) contains a 27 amino acid putative signal sequence followed by a mature protein of 264 amino acids with 18 cysteine residues clustered near the N- and C-terminus. Accordingly, expression of the cloned IGFBP-3 cDNA in mammalian tissue culture cells results in secretion of the protein into the culture medium. IGFBP-3 shares high homology (33% amino acid identity) including conservation of all 18 cysteine residues with a smaller human IGF-binding protein (BP-28) identified in amniotic fluid.


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