IL15RA Antibody 1 Publications

Rabbit Polyclonal| Catalog number: 16744-1-AP

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Freight/Packing

Con: 35 μg/150 μl

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Species specificity:
human

Positive WB detected in:
HeLa cells

Positive IHC detected in:
human liver tissue, human brain tissue, human heart tissue, human kidney tissue, human liver tissue, human skin tissue, human spleen tissue, human testis tissue

Recommended dilution:
WB : 1:500-1:1000
IHC : 1:20-1:200

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
interleukin 15 receptor, alpha

Calculated molecular weight:
231aa,24 kDa

Observed molecular weight:
55-65 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
IL15RA

Synonyms
IL 15 receptor subunit alpha, IL 15R alpha, IL 15RA, IL15RA, interleukin 15 receptor, alpha, sIL 15 receptor subunit alpha, sIL 15R alpha, sIL 15RA
Background

Interleukin-15 (IL-15) is a pleiotropic cytokine that plays an important role in both innate and adaptive immunity. IL-15 is mainly produced by activated monocytes, macrophages and dendritic cells, and is structurally similar to IL-2 (PMID: 8178155; 12401478). These two cytokines share the same IL-2/15Rβ and common γ-chain receptor subunits. In addition, IL-2 and IL-15 have their own private α-chain receptor subunit, IL-2Rα and IL-15Rα, respectively (PMID: 7641685). The IL-15Rα chain is expressed by many cell types including monocytes, DCs, NK, T cells and fibroblasts. Several isoforms of IL-15Rα exist and are generated either by alternative splicing or by proteolytic cleavage (PMID: 10480910; 15265897).


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