IL20 Antibody 0 Publications

Rabbit Polyclonal| Catalog number: 18104-1-AP

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Freight/Packing

Con: 62 μg/150 μl

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Species specificity:
human

Positive WB detected in:
Transfected HEK-293 cells

Recommended dilution:
WB : 1:500-1:1000

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
interleukin 20

Calculated molecular weight:
406aa,44 kDa

Observed molecular weight:

GenBank accession number:

Gene ID (NCBI):

Gene symbol
IL20

Synonyms
Cytokine Zcyto10, IL 20, IL20, interleukin 20, ZCYTO10
Background

Interleukin-20 (IL-20) is a protein belonging to the IL-10 family of cytokines. IL-20 receptor (IL-20R) and IL-20 are expressed in several normal tissue types, including the lung, skin, and kidney. IL-20 is a cytokine structurally related to interleukin 10. IL-20 is produced by activated keratinocytes and monocytes and transmits an intracellular signal through two distinct cell-surface receptor complexes on keratinocytes and other epithelial cells. IL-20 can stimulate STAT3 activation in keratinocytes. IL-20 regulates proliferation and differentiation of keratinocytes during inflammation, particularly inflammation associated with the skin. In addition, IL-20 also causes cell expansion of multipotential hematopoietic progenitor cells. IL-20 is highly associated with potent inflammatory diseases such as psoriasis, contact hypersensitivity, rheumatoid arthritis, and atherosclerosis.


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