IL22RA2 Antibody 0 Publications

Rabbit Polyclonal| Catalog number: 22861-1-AP

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Freight/Packing

Con: 49 μg/150 μl

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Species specificity:
human

Positive WB detected in:
MDA-MB-453s cells

Positive IHC detected in:
human lung cancer tissue,human breast cancer tissue

Positive FC detected in:
HeLa cells

Recommended dilution:
WB : 1:500-1:1000
IHC : 1:50-1:500

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
interleukin 22 receptor, alpha 2

Calculated molecular weight:
263aa,31 kDa

Observed molecular weight:
27 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
IL22RA2

Synonyms
CRF2 10, CRF2 S1, CRF2X, IL 22 receptor subunit alpha 2, IL 22BP, IL 22R alpha 2, IL 22RA2, IL22BP, IL22RA2, Interleukin 22 binding protein, ZcytoR16
Background

Interleukin-22 receptor subunit alpha-2 (IL22RA2, also known as CRF2-10) is a soluble member of the type II cytokine receptor family. Through binding to IL22, IL22RA2 prevents the interaction of IL22 with the functional IL22-R complex and blocks the activity of IL22 (in vitro). IL22RA2 may play an important role as an IL22 antagonist in the regulation of inflammatory responses. It has been described that human IL22RA2 gene encodes three alternatively spliced isoforms called CRF2-10L, CRF2-10, and CRF2-10s, with molecular weights of 31 kDa, 27 kDa, and 15 kDa, respectively.


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