CD127/IL7R Antibody 0 Publications

Rabbit Polyclonal| Catalog number: 17626-1-AP

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Freight/Packing

Con: 22 μg/150 μl

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Species specificity:
human, mouse

Positive WB detected in:
mouse thymus tissue, K-562 cells

Positive IP detected in:
K-562 cells

Positive FC detected in:
K-562 cells

Recommended dilution:
WB : 1:500-1:3600
IP : 0.5-4.0 ug for IP and 1:500-1:2000 for WB

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
interleukin 7 receptor

Calculated molecular weight:
459aa,52 kDa

Observed molecular weight:
56-58 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
IL7R

Synonyms
CD127, CDW127, IL 7 receptor subunit alpha, IL 7R alpha, IL 7R subunit alpha, IL 7RA, IL7R, IL7RA, ILRA, interleukin 7 receptor
Background

CD127, also known as IL-7R subunit alpha (IL-7RA), is a type I membrane glycoprotein expressed on thymocytes, B cell precursors, most T cells, and some lymphoid and myeloid cells. IL-7R is a heterodimer composed of CD127 and the common-γ chain receptor (CD132). IL-7R plays critical roles in lymphocyte development and homeostasis. CD127 can also act as a receptor for thymic stromal lymphopoietin (TSLP).


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