ING2 Antibody 0 Publications

Mouse Monoclonal| Catalog number: 66512-1-Ig |CloneNo.: 2C3A7

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Freight/Packing

Con: 150 μg/150 μl

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Species specificity:
Human, rat, mouse

Positive WB detected in:
HSCT6 cells, T-47D cells, NIH/3T3 cells

Recommended dilution:
WB : 1:1000-1:6000

Product Information


Source:
Mouse

Purification method:
Protein A purification

Isotype:
IgG1

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
inhibitor of growth family, member 2

Calculated molecular weight:
280aa,33 kDa

Observed molecular weight:
33-35 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
ING2

Synonyms
ING1L, ING1Lp, ING2, Inhibitor of growth protein 2, p32, p33ING2
Background

ING2, also named as ING1L, belongs to the ING family and contains a PHD-type zinc finger. It is induced by the DNA-damaging agents etoposide and neocarzinostatin. As a candidate tumor suppressor, ING2 seems to be involved in p53/TP53 activation and p53/TP53-dependent apoptotic pathways, probably by enhancing acetylation of p53/TP53. It is a component of a mSin3A-like corepressor complex, which is probably involved in deacetylation of nucleosomal histones. Recent finding reported that ING2 regulates muscle differentiation by regulating chormatin remodeling program.


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