Inhibin Beta A Polyclonal antibody

Inhibin Beta A Polyclonal Antibody for IF, IHC, WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human and More (1)

Applications

WB, IHC, IF, ELISA

Conjugate

Unconjugated

Cat no : 10651-1-AP

Synonyms

Activin beta A chain, EDF, FRP, INHBA, Inhibin beta A chain, Inhibin β-A, inhibin, beta A



Tested Applications

Positive WB detected inHeLa cells, A549 cells, BGC-823 cells, SGC-7901 cells, MCF-7 cells, HepG2 cells
Positive IHC detected inhuman lung cancer tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0
Positive IF detected inA549 cells

Recommended dilution

ApplicationDilution
Western Blot (WB)WB : 1:500-1:1000
Immunohistochemistry (IHC)IHC : 1:20-1:200
Immunofluorescence (IF)IF : 1:20-1:200
Sample-dependent, check data in validation data gallery

Product Information

10651-1-AP targets Inhibin Beta A in WB, IHC, IF, ELISA applications and shows reactivity with human samples.

Tested Reactivity human
Cited Reactivity human, mouse
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen Inhibin Beta A fusion protein Ag1001
Full Name inhibin, beta A
Calculated molecular weight 47 kDa
Observed molecular weight 47 kDa
GenBank accession numberBC007858
Gene symbol INHBA
Gene ID (NCBI) 3624
Conjugate Unconjugated
Form Liquid
Purification Method Antigen affinity purification
Storage Buffer PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Background Information

Inhibin is a 32-kD dimeric glycoprotein consisting of an alpha subunit and one of two beta subunits (beta A or beta B) leading to inhibin A or B, respectively, which was isolated and cloned on the basis of its ability to inhibit FSH release from the pituitary. Inhibin beta A forms a disulfide-linked homo-dimer known as activin A, which has been implicated in multiple biologic processes, including neoplastic progression. The inhibin beta A can also bind the beta B and A isoforms to form activin AB and inhibin, respectively.

Protocols

Product Specific Protocols
WB protocol for Inhibin Beta A antibody 10651-1-APDownload protocol
IHC protocol for Inhibin Beta A antibody 10651-1-APDownload protocol
IF protocol for Inhibin Beta A antibody 10651-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

Publications

SpeciesApplicationTitle
humanIHC

Oncotarget

Gender differences in fibrosis remodeling in patients with long-standing persistent atrial fibrillation.

Authors - Zhi Li
humanIHC

Cancer Biomark

Evaluation of protein expression pattern of stanniocalcin 2, insulin-like growth factor-binding protein 7, inhibin beta A and four and a half LIM domains 1 in esophageal squamous cell carcinoma.

Authors - Kashyap Manoj Kumar MK
mouseIHC

Evid Based Complement Alternat Med

Polysaccharides of Fructus corni Improve Ovarian Function in Mice with Aging-Associated Perimenopause Symptoms.

Authors - Yong Wang
humanWB, IHC

Dis Markers

Targeting INHBA in Ovarian Cancer Cells Suppresses Cancer Xenograft Growth by Attenuating Stromal Fibroblast Activation.

Authors - Xiaoting Li

BMC Cancer

Esophageal squamous cell carcinoma invasion is inhibited by Activin A in ACVRIB-positive cells.

Authors - Holli A Loomans

Hepatol Commun

Activin A is a prominent autocrine regulator of hepatocyte growth arrest.

Authors - Srividyameena Haridoss