MUM1/IRF4 Antibody 1 Publications

Rabbit Polyclonal| Catalog number: 11247-2-AP

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Freight/Packing

Con: 66 μg/150 μl

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Species specificity:
human, mouse

Positive WB detected in:
mouse spleen tissue, Jurkat cells, mouse lung tissue, mouse thymus tissue, Raji cells

Positive IP detected in:
mouse spleen tissue

Positive IHC detected in:
human lymphoma tissue, human tonsillitis tissue

Positive FC detected in:
Raji cells

Recommended dilution:
WB : 1:500-1:2000
IP : 0.5-4.0 ug for IP and 1:500-1:1000 for WB
IHC : 1:20-1:200

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
interferon regulatory factor 4

Calculated molecular weight:
52 kDa

Observed molecular weight:
52 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
IRF4

Synonyms
interferon regulatory factor 4, IRF 4, IRF4, LSIRF, Multiple myeloma oncogene 1, MUM1, NF EM5
Background

Interferon regulatory factor 4 (IRF4) is a member of the IRF family of transcription factors, expressed in most cell types of the immune system. IRF4 is a transcription factor essential for the development of T helper-2 (Th2) cells, IL17-producing Th17 cells, and IL9-producing Th9 cells, as well as dendritic cell (DC). It binds to and activates the interferon-stimulated response element (ISRE) of the MHC class I promoter, and may have a role in ISRE-targeted signal transduction mechanisms specific to lymphoid cells.


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