ISYNA1 Antibody 2 Publications

Rabbit Polyclonal| Catalog number: 14142-1-AP

  • Print page
  • Download PDF

Be the first to review this product



Con: 35 μg/150 μl

Choose size:

Please visit your regions distributor:

Species specificity:
human, mouse, rat

Positive WB detected in:
HepG2 cells

Positive IHC detected in:
human pancreas cancer tissue

Positive IF detected in:
HepG2 cells

Recommended dilution:
WB : 1:500-1:1000
IHC : 1:20-1:200
IF : 1:20-1:200

Product Information


Purification method:
Antigen affinity purification


PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information

Full name:
inositol-3-phosphate synthase 1

Calculated molecular weight:
61 kDa

Observed molecular weight:
61 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol

hINO1, hIPS, Ino1, INOS, IPS, IPS 1, ISYNA1, MI 1 P synthase, MIP synthase

Myo-inositol 3-phosphate synthase (ISYNA1/IP synthase) is a rate-limiting enzyme that catalyzes the first step in the biosynthesis of all inositol containing compounds. It converts glucose 6-phosphate to Myo-inositol 3-phosphate.(PMID:21841945). The native enzyme is typically a homotrimermade up of 68-kDa subunits in mammalian cells and a homotetramer in yeast and plant cells. There are three new isoforms of 62, 43, and 16kDa detected suggesting ISYNA1 is a completely different holoenzyme. But only the brain and testis manifest the 68-kDa isoform, whereas the pancreas has a slightly smaller isoformat 67 kDa. The intestine has a completely unique isoformprofile comprising 62,43, 20kDa isoforms(PMID:19188364).

to top