KCNN4 Monoclonal antibody

KCNN4 Monoclonal Antibody for WB, ELISA

Host / Isotype

Mouse / IgG2a

Reactivity

human, mouse, rat

Applications

WB, ELISA

Conjugate

Unconjugated

CloneNo.

2A6G5

Cat no : 60276-1-Ig

Synonyms

hIKCa1, hKCa4, hSK4, IK1, IKCA1, KCa3.1, KCA4, KCNN4, Putative Gardos channel, SK4, SKCa 4, SKCa4



Tested Applications

Positive WB detected inhuman blood tissue

Recommended dilution

ApplicationDilution
Western Blot (WB)WB : 1:500-1:2000
Sample-dependent, check data in validation data gallery

Published Applications

WBSee 1 publications below

Product Information

60276-1-Ig targets KCNN4 in WB, ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Reactivity human, mouse, rat
Cited Reactivity rat
Host / Isotype Mouse / IgG2a
Class Monoclonal
Type Antibody
Immunogen KCNN4 fusion protein Ag19774
Full Name potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4
Calculated molecular weight 427 aa, 48 kDa
Observed molecular weight 48 kDa
GenBank accession numberBC015337
Gene symbol KCNN4
Gene ID (NCBI) 3783
Conjugate Unconjugated
Form Liquid
Purification Method Protein A purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Background Information

The intermediate conductance calcium-activated potassium channel KCNN4, also known as KCa3.1, IK1, or SK4, is a member of the potassium channel KCNN family. KCNN4 is expressed in T cells, mast cells, macrophages, erythrocytes, vascular smooth muscle cells, airway smooth muscle cells, intestinal and airway epithelial cells (PMID: 19681865; 21493782). Functionally, KCNN4 plays a key role in calcium-dependent cell functions, such as proliferation, activation, and migration, in a broad range of cell types (PMID: 21493782).

Protocols

Product Specific Protocols
WB protocol for KCNN4 antibody 60276-1-IgDownload protocol
Standard Protocols
Click here to view our Standard Protocols

Publications

SpeciesApplicationTitle
ratWB

Acta Cardiol Sin

PMID: 29167619

Authors - Peng Dong