KIF3A Antibody 2 Publications

Rabbit Polyclonal| Catalog number: 13930-1-AP

Featured Product KD/KO validated

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Freight/Packing

Con: 29 μg/150 μl

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Species specificity:
human, mouse

Positive WB detected in:
mouse brain tissue, human cerebellum tissue, mouse cerebellum tissue

Positive IP detected in:
mouse brain tissue

Positive IHC detected in:
human gliomas tissue

Recommended dilution:
WB : 1:500-1:2000
IP : 0.5-4.0 ug for IP and 1:500-1:1000 for WB
IHC : 1:20-1:200

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
kinesin family member 3A

Calculated molecular weight:
80 kDa

Observed molecular weight:
80 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
KIF3A

Synonyms
KIF3, KIF3A, kinesin family member 3A, Kinesin like protein KIF3A
Background

KIF3A is a subunit of Kinesin II that is essential for intraflagellar transport (IFT). It functions as the anterograde motor to deliver ciliary components to the tip where the axoneme is assembled. Disruption of KIF3A has been reported to block mammalian ciliogenesis. Recently KIF3A has been found to localize to the mother centriole and is required for centrioles organization. This antibody specifically recognizes the endogenous KIF3A protein in mouse embryonic fibroblasts (MEFs) but not in KIF3A-/- lysate. (23386061)


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