KRT2-specific Antibody 0 Publications

Rabbit Polyclonal| Catalog number: 16849-1-AP

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Freight/Packing

Con: 0 μg/150 μl

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Tested Applications

Applications:
ELISA
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Species specificity:
human, mouse

Recommended dilution:

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Immunogen:
Peptide

Full name:
keratin 2

Calculated molecular weight:
65 kDa

Observed molecular weight:

GenBank accession number:

Gene ID (NCBI):

Gene symbol
KRT2

Synonyms
KRT2, Keratin 2e, K2e, KRTE, Type II keratin Kb2
Background

Keratins are a large family of proteins that form the intermediate filament cytoskeleton of epithelial cells. Keratin expression is highly regulated, tissue specific, and varies according to cell-state. Type I keratins consist of acidic, low molecular weight proteins with MW ranging from 40 kDa (KRT19) to 64 kDa (KRT9). Type 2 keratins consist of basic or neutral, high molecular weight proteins with MW from 52 kDa (KRT8) to 67 kDa (KRT18).Keratin 2 is a type II cytokeratin. It is found largely in the upper spinous layer of epidermal keratinocytes, and also in other regions, notably the epidermis covering the knee, thigh, and groin. This antibody is specifically against Keratin 2. It does not cross react with other keratins.


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