LARP7 Antibody 5 Publications

Rabbit Polyclonal| Catalog number: 17067-1-AP

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Freight/Packing

Con: 20 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
HeLa cells, human brain tissue, mouse liver tissue

Positive IHC detected in:
human kidney tissue, human liver tissue, human ovary tissue, human placenta tissue, human skin tissue, human spleen tissue, human testis tissue

Positive IF detected in:
HeLa cells

Recommended dilution:
WB : 1:500-1:2000
IHC : 1:20-1:200
IF : 1:50-1:500

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
La ribonucleoprotein domain family, member 7

Calculated molecular weight:
582aa,67 kDa

Observed molecular weight:
67 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
LARP7

Synonyms
DKFZp564K112, HDCMA18P, La related protein 7, LARP7, PIP7S
Background

LARP7 belongs to the LARP RNA-binding protein family, which includes the lupus LA antigen gene, and modulates the metabolism and function of a variety of RNA species [PMID:20138158]. LARP7 binds to the 7SK RNP complex, and sequesters the positive transcription elongation factor b (P-TEFb) in an inactive form, preventing RNA polymerase II phosphorylation and subsequent transcriptional elongation. binds to and stabilizes 7sk snRNA[PMID:19416841].


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