LBR Antibody 2 Publications

Rabbit Polyclonal| Catalog number: 12398-1-AP

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Freight/Packing

Con: 32 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
A375 cells, human brain tissue

Positive IP detected in:
A375 cells

Positive IF detected in:
Hela cells, HeLa cells, HepG2 cells

Positive FC detected in:
Jurkat cells

Recommended dilution:
WB : 1:1000-1:4000
IP : 0.5-4.0 ug for IP and 1:500-1:1000 for WB
IF : 1:10-1:100

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
lamin B receptor

Calculated molecular weight:
615aa,71 kDa

Observed molecular weight:
58 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
LBR

Synonyms
DHCR14B, FLJ43126, lamin B receptor, LBR, LMN2R, PHA
Background

Lamin-B receptor (LBR) belongs to the ERG4/ERG24 family. LBR is a 58-kDa integral protein of the nuclear envelope inner membrane and anchors the lamina and the heterochromatin to the inner nuclear membrane. LBR may mediate interaction between chromatin and lamin B. Mutations of the LBR gene has been associated with autosomal recessive HEM/Greenberg skeletal dysplasia.


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