DNA Ligase I Antibody 4 Publications

Rabbit Polyclonal| Catalog number: 18051-1-AP

Featured Product KD/KO validated

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Freight/Packing

Con: 21 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
HepG2 cells, A431 cells, HeLa cells, Jurkat cells

Positive IP detected in:
HepG2 cells

Positive IHC detected in:
human spleen tissue, human brain tissue, human placenta tissue, human testis tissue

Recommended dilution:
WB : 1:500-1:3000
IP : 0.5-4.0 ug for IP and 1:500-1:1000 for WB
IHC : 1:20-1:200

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
ligase I, DNA, ATP-dependent

Calculated molecular weight:
919aa,102 kDa

Observed molecular weight:
130 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
LIG1

Synonyms
DNA ligase 1, DNA Ligase I, LIG1, ligase I, DNA, ATP dependent
Background

LIG1, also named as LRIG1, acts as a feedback negative regulator of signaling by receptor tyrosine kinases, through a mechanism that involves enhancement of receptor ubiquitination and accelerated intracellular degradation.

Read more about this antibody on the blog: http://blog.ptglab.com/index.php/proteintechs-anti-neil3-antibody-used-investigate-mechanisms-of-dna-repair/?preview=true


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