LNX1 Antibody 0 Publications

Rabbit Polyclonal| Catalog number: 13124-1-AP

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Con: 20 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
mouse testis tissue, mouse kidney tissue

Recommended dilution:
WB : 1:500-1:2400

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
ligand of numb-protein X 1

Calculated molecular weight:
728aa,81 kDa

Observed molecular weight:
70 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
LNX1

Synonyms
ligand of numb protein X 1, LNX, LNX1, MPDZ, Numb binding protein 1, PDZRN2
Background

LNX1 (Ligand of Numb, protein X 1) was originally identified as a binding partner of the cell-fate determinant Numb and was reported to be involved in ubiquitylation and degradation of Numb. LNX1 contains four PDZ domains and may function as a scaffold for a multi-protein complex. LNX1 has two splicing variants, LNX1p70 and LNX1p80. LNX1p70 has the N-terminal Numb binding region and four PDZ domains, whereas LNX1p80 has an additional RING-finger domain at the N-terminus followed by a Numb-binding region and four PDZ domains. This antibody can detect both LNX1p70 and LNX1p80, around 70-80 kDa and 80-100 kDa, respectively.


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