Lactoferrin Antibody 0 Publications

Rabbit Polyclonal| Catalog number: 10933-1-AP

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Freight/Packing

Con: 46 μg/150 μl

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Species specificity:
human

Positive WB detected in:
HEK-293 cells, human pancreas tissue

Positive IP detected in:
HeLa cells

Positive IHC detected in:
human liver tissue, human liver tissue, human prostate hyperplasia tissue

Recommended dilution:
WB : 1:500-1:1000
IP : 0.5-4.0 ug for IP and 1:500-1:1000 for WB
IHC : 1:20-1:200

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
lactotransferrin

Calculated molecular weight:
80 kDa

Observed molecular weight:
51 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
LTF

Synonyms
GIG12, HLF2, Lactoferrin, lactotransferrin, LF, LTF, Talalactoferrin
Background

LTF(Lactotransferrin) is also named as GIG12, LF and belongs to the transferrin family. It is an iron binding transport protein which can bind two atoms of ferric iron in association with the binding of an anion, usually bicarbonate. LTF is also an important protein component of the innate immune system that is broadly distributed within the body fluids. It can contribute to the activation of both the innate and adaptive immune responses by promoting the recruitment of leukocytes and activation of dendritic cells(PMID:18453607). This protein has 2 isoforms produced by alternative promoter usage. The human LTF can be isolated two fragments, an N-terminal tryptic fragment having an Mr of 30 kDa and a C-terminal tryptic fragment having an Mr of 50 kDa by a mild tryptic digest(PMID:3790094).


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