LYPLA1 Antibody 1 Publications

Rabbit Polyclonal| Catalog number: 16055-1-AP

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Freight/Packing

Con: 32 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
HeLa cells, human brain tissue, human liver tissue, mouse brain tissue, rat brain tissue, rat liver tissue

Positive IP detected in:
mouse brain tissue

Positive IHC detected in:
human colon cancer tissue

Positive IF detected in:
HeLa cells

Recommended dilution:
WB : 1:500-1:2000
IP : 0.5-4.0 ug for IP and 1:500-1:1000 for WB
IHC : 1:20-1:200
IF : 1:50-1:500

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
lysophospholipase I

Calculated molecular weight:
230aa,25 kDa

Observed molecular weight:
25 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
LYPLA1

Synonyms
Acyl protein thioesterase 1, APT 1, APT1, hAPT1, LPL I, LPL1, LYPLA1, Lysophospholipase 1, lysophospholipase I, LYSOPLA, LysoPLA I
Background

LYPLA1(Lysophospholipase 1) is also named as APT1(Acyl-protein thioesterase 1), LPL1 and belongs to the AB hydrolase 2 family. It is an important enzyme responsible for depalmitoylation of palmitoyl proteins and works as a thioesterase that cleaves the S-palmitoyl group of H-Ras, heterotrimeric G protein alfa subunit (Ga) , regulator of G protein signaling 4 (RGS4) and the endothelial isoform of nitric oxide synthase (eNOS) in vitro(PMID:19439193).


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