MAD1 Antibody 0 Publications

Rabbit Polyclonal| Catalog number: 18322-1-AP

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Freight/Packing

Con: 32 μg/150 μl

Choose size:

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Species specificity:
human, mouse, rat

Positive WB detected in:
A431 cells, HeLa cells, HepG2 cells, human brain tissue, Raji cells

Positive IP detected in:
HeLa cells

Positive IHC detected in:
human brain tissue, human brain tissue, human kidney tissue, human ovary tissue, human placenta tissue, human skin tissue, human spleen tissue, human testis tissue

Positive IF detected in:
SH-SY5Y cells, A431 cells

Recommended dilution:
WB : 1:500-1:3000
IP : 0.5-4.0 ug for IP and 1:500-1:2000 for WB
IHC : 1:20-1:200
IF : 1:20-1:200

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
MAD1 mitotic arrest deficient-like 1 (yeast)

Calculated molecular weight:
83 kDa

Observed molecular weight:
83 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
MAD1L1

Synonyms
hMAD1, HsMAD1, MAD1, MAD1 like protein 1, MAD1L1, PIG9, Tax binding protein 181, TP53I9, TXBP181
Background

MAD1L1 is a component of the spindle-assembly checkpoint that prevents the onset of anaphase until all chromosomes are properly aligned at the metaphase plate. It recruits MAD2L1 to unattached kinetochores. Also it is required for anchoring MAD2L1 to the nuclear periphery. In addition, it binds to the TERT promoter and represses telomerase expression, possibly by interfering with MYC binding [PMID:10049595, 12837246].


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