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MDM2 Antibody 5 Publications

Rabbit Polyclonal| Catalog number: 19058-1-AP

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Con: 32 μg/150 μl

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Tested Applications
Applications:
ELISA, WB
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19058-1-AP;A431 cells

A431 cells were subjected to SDS PAGE followed by western blot with 19058-1-AP( MDM2 Antibody) at dilution of 1:300 incubated at 4 degree celsius over night

Species specificity:
human, mouse, rat
Positive WB detected in:
A431 cells, A549 cells, MCF-7 cells
Recommended dilution:
WB : 1:200-1:1000

Product Information

Source:
Rabbit
Purification method:
Antigen affinity purification
Isotype:
IgG
Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information

Immunogen:
Peptide
Full name:
Mdm2 p53 binding protein homolog (mouse)
Calculated molecular weight:
55 kDa
Observed molecular weight:
30-55 kDa
GenBank accession number:
NM_002392
Gene ID (NCBI):
4193
Gene symbol
MDM2
Synonyms
Double minute 2 protein, hdm2, HDMX, MDM2, Oncoprotein Mdm2, p53 binding protein Mdm2
Background

MDM2 belongs to the MDM2/MDM4 family. It inhibits TP53/p53- and TP73/p73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain. MDM2 can bind to the p53 tumor suppressor protein and negatively regulate its functions in transcription, cell cycle arrest, and apoptosis. Human mdm2 has a calculated molecular mass of 54 kDa.


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