MKP-2 Antibody 0 Publications

Mouse Monoclonal| Catalog number: 66349-1-Ig |CloneNo.: 1G1C12

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Freight/Packing

Con: 150 μg/150 μl

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Species specificity:
human, pig, rat, mouse

Positive WB detected in:
rat brain tissue, HepG2 cells, NIH/3T3 cells, pig brain tissue, RAW 264.7 cells

Positive IHC detected in:
human breast cancer tissue, human breast cancer tissue, human colon cancer tissue

Positive IF detected in:
HepG2 cells

Recommended dilution:
WB : 1:500-1:2000
IHC : 1:50-1:500
IF : 1:50-1:500

Product Information


Source:
Mouse

Purification method:
Protein G purification

Isotype:
IgG1

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
dual specificity phosphatase 4

Calculated molecular weight:
43 kDa

Observed molecular weight:
43 kDa, 33 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
DUSP4

Synonyms
dual specificity phosphatase 4, DUSP4, HVH2, MAP kinase phosphatase 2, MKP 2, MKP2, MKP-2, TYP, VH2
Background

DUSP4, also named as MKP-2, is a member of the mitogen-activated protein (MAP) kinase phosphatase family which has been suggested to play an important role in the feedback control of MAP kinase-mediated gene expression. DUSP4 preferentially inactivates ERK1, ERK2 and JNK, is expressed in a variety of tissues, and is localized in the nucleus. DUSP4 encodes two distinct isoforms: MKP-2-L(43 kDa) and MKP-2-S (33 kDa).


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