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MYD88 Antibody 17 Publications

Rabbit Polyclonal| Catalog number: 23230-1-AP

Featured Product KD/KO validated

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Con: 35 μg/150 μl

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Tested Applications

Applications:
WB, IHC, ELISA
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MYD88 Antibody WB MCF-7 cells 23230-1-AP

MCF-7 cells were subjected to SDS PAGE followed by western blot with 23230-1-AP (MYD88 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours

Species specificity:
human, rat, African green monkey kidney, mouse, sheep
Positive WB detected in:
MCF-7 cells, A549 cells, Jurkat cells, rat liver tissue
Recommended dilution:
WB : 1:500-1:2000

Protocols

Product-specific protocols

Standard Protocols

Product Information

Source:
Rabbit
Purification method:
Antigen affinity purification
Isotype:
IgG
Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information

Immunogen:
MYD88 fusion protein Ag19770
Full name:
myeloid differentiation primary response gene (88)
Calculated molecular weight:
33 kDa
Observed molecular weight:
33 kDa
GenBank accession number:
BC013589
Gene ID (NCBI):
4615
Gene symbol
MYD88
Synonyms
MYD88, MYD88D

Background

MYD88 is a cytosolic adapter protein that plays a central role in the innate and adaptive immune response. MYD88 is the key adaptor protein for the interleukin-1 receptor (IL-1R) and most Toll-like receptors (TLRs), which are essential for innate immunity and pathogen-associated molecular pattern recognition. Mutations in the MyD88 gene lead to the development of cancer in humans and mice suggesting that MyD88 also plays a cell autonomous role in tissue homeostasis.


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