MYO18A Antibody 4 Publications

Rabbit Polyclonal| Catalog number: 14611-1-AP

Featured Product KD/KO validated

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Freight/Packing

Con: 26 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
Jurkat cells, HeLa cells, K-562 cells, Neuro-2a cells, NIH/3T3 cells

Positive IP detected in:
HeLa cells

Recommended dilution:
WB : 1:1000-1:6000
IP : 0.5-4.0 ug for IP and 1:200-1:1000 for WB

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
myosin XVIIIA

Calculated molecular weight:
233 kDa

Observed molecular weight:
230 kDa,190 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
MYO18A

Synonyms
CD245, DKFZp686L0243, KIAA0216, MAJN, MYO18A, Myosin containing a PDZ domain, myosin XVIIIA, MYSPDZ, SPR210
Background

MYO18A is an unconventional myosin that may play a role in the stabilization and organization of the actin cytoskeleton. Recently MYO18A has been identified as the receptor of SP and is responsible for clearance of SP-A-opsonized bacteria in in vivo infection. Two different isoforms of mouse Myo18A have been identified: Myo18A-alpha and Myo18A-beta as 230- and 190-kD proteins, respectively.Myo18a-alpha colocalizes with the ER-Golgi complex and with membrane ruffles and filopodia, while Myo18a-beta localizes diffusely to the cytoplasm.


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